Canine Elliptocytosis
Canine Elliptocytosis is a rare genetic disease causing the red blood cells to be abnormally elliptical in shape, rather than round. It generally does not cause a clinical problem to affected dogs, but puppies may be mildly anaemic and smaller than others. There is a DNA test available to identify if a breeding dog is carrying this disease.
Congenital Dry Eye
Congenital Dry Eye is a genetic cause of severe eye problems in Cavalier King Charles Spaniel puppies. This disease is linked to Curly Coat Syndrome. Congenital Dry Eye is different from Acquired Dry Eye, which is a less severe eye disease that can develop in older dogs of many breeds. There is a DNA test available to identify if breeding Cavaliers are carrying Congenital Dry Eye or Curly Coat.
(CM)
Congenital Macrothrombocytopenia (CM) is a mild disease which normally does not have any impact on an affected dog’s health or lifespan but can cause concern if noticed on routine bloodwork without knowing the cause. It is a blood disease resulting in low numbers of very large platelets. There is a DNA test available to identify if a breeding dog is carrying this condition.
Curly Coat
This is a genetic condition affecting Cavalier King Charles Spaniels that causes severe skin, nail and eye issues, as well as making the usually long smooth coat tight and curly. Curly Coat is linked to Congenital Dry Eye disease. There is a DNA test available to identify if breeding Cavaliers are carrying Congenital Dry Eye or Curly Coat.
Degenerative Myelopathy (DM)
This is a disease affecting the spinal cord of older dogs, initially causing wobbliness and eventually hindlimb paralysis. It can affect a wide range of breeds. There is now a DNA test that can indicated if a breeding dog is carrying this disease.
Episodic Falling Syndrome
This is a genetic neurological condition affecting Cavalier King Charles Spaniels. It causes sudden stiffening of the legs, often causing the dog to fall over and be unable to move. There is a DNA test available to indicate if a breeding dog is carrying this disease. The test is also recommended in Cavoodles.
GM2
GM2 gangliosidosis is a lysosomal storage disorder that causes neurological problems. There are a few different types of this disease affecting different breeds. There is a DNA test available to identify if a breeding dog is carrying this condition.
MPS
ucopolysaccharidosis is a genetic lysosomal storage disease that can cause various problems including stunted growth and bone deformities. There are a few different variants of this disease that have been identified in different breeds. For many breeds there are DNA tests available to identify if a breeding dog is carrying the condition.